2 DAY ONLINE HANDS-ON WORKSHOP
Gene Expression Profiling and Pathway Enrichment Analysis
Unveiling Biological Insights
- November 23-24, 2024 | 11:00 AM - 01:30 PM IST
Intensive Learning
Hands-On Exercise
Interactive Sessions
Individual Practice
Introduction to Workshop
Gene Expression Profiling and Pathway Enrichment Analysis are essential tools in modern genomics, providing deep insights into the molecular mechanisms underlying various biological processes and diseases. By examining gene expression profiles, researchers can measure the activity levels of thousands of genes simultaneously, identifying which genes are upregulated or downregulated under specific conditions.
Gene expression profiling offer a snapshot of the cellular state, revealing how genes respond to internal and external stimuli. This information is crucial for understanding complex biological phenomena, such as cell differentiation, disease progression, and response to treatments. However, the sheer volume of data generated can be overwhelming, necessitating robust analytical methods to extract meaningful insights.
Pathway enrichment analysis addresses this challenge by mapping differentially expressed genes to known biological pathways. This process identifies pathways that are significantly impacted by changes in gene expression, providing a functional context for the observed gene expression profiles. By linking genes to pathways, researchers can pinpoint key regulatory networks and molecular mechanisms driving the observed changes.
Applications of Gene Expression Profiles and Pathway Enrichment Analysis
In this section we are discussing some of the potential areas of application of Gene Expression Profiling and Pathway Enrichment Analysis & how it can be helpful in these areas to carryout analysis.
Cancer Research and Treatment
Gene expression profiles and pathway enrichment analysis are crucial in cancer research for identifying differentially expressed genes between tumor and normal tissues.
Drug Discovery and Development
In pharmacogenomics, gene expression profiling and pathway enrichment analysis are employed to understand how different drugs affect gene expression and biological pathways.
Understanding Genetic Diseases
Gene expression profiles and pathway enrichment analysis are instrumental in studying genetic disorders.
Immune Response Profiling
These tools are used to study the immune response to infections, vaccines, and autoimmune diseases.
Developmental Biology
Gene expression profiling and pathway enrichment analysis are applied to understand the complex processes of development and differentiation.
Different Types of Analysis
Majorly, there are 3 different types of analysis using Gene Expression Profiling and Pathway Enrichment Analysis so below we have tried to list them down to help you take better decision if this masterclass will be relevant for your learning and be helpful in your intended area of research.
Differential Gene Expression
Differential gene expression analysis involves comparing gene expression profiles between different conditions, such as diseased vs. healthy tissues or treated vs. untreated samples.
Co-expression Network
Co-expression network analysis examines the correlation patterns between gene expression profiles across different samples to identify groups of genes that are co-regulated.
Time-series Expression
Time-series expression analysis tracks changes in gene expression over time, providing insights into dynamic biological processes such as development, response to treatment.
Detailed Agenda of The Workshop
Combining gene expression profiling and pathway enrichment analysis enhances our understanding of biological systems, leading to discoveries that can inform diagnostics, treatment strategies, and the development of new therapies. This powerful combination continues to drive advancements in genomics, offering a clearer view of the intricate web of gene regulation and cellular function.
Topics Covered
- Install Necessary Packages
- Quality Control and Trimming
- Mapping Reads to Reference Genome
- Counting Reads
- Differential Expression Analysis in R
- Normalization and Visualization
- Hierarchical Clustering
- GO and KEGG Pathway Enrichment Analysis
Take Away From The Workshop
Gene Expression Profiling and Pathway Enrichment Analysis are indispensable for interpreting complex genomic data, uncovering the molecular basis of health and disease, and paving the way for innovative biomedical research and personalized medicine.
Apart from the topics mentioned above there are a few extra things which you can take away from this bootcamp, which will be adding more value to your work
An introductory theory document to help you better understand the subject will also be provided.
After the completion of the session complete access to the trainers slide deck will also be provided
We will also be providing a complete access to trainers repository so that you can use it as reference later
During the course of 3 days we will be have live8+ hourse of training sessions with the participants.
Hands-On exercises are a must to better learn any technology and be able to reproduce it later.
A Participations certificate is a must after successfully completing the training as a sign of accomplishment.
Expected Outcomes of the Workshop
After completing all the tasks of this masterclass all of our participants will be able to:
One of the primary outcomes of gene expression profiles and pathway enrichment analysis is the identification of key biomarkers.
Gene expression profiles and pathway enrichment analysis can uncover potential drug targets by identifying genes and pathways
This analysis helps elucidate the underlying molecular mechanisms of diseases by identifying differentially expressed genes.
This knowledge is essential for developing strategies that target multiple genes or pathways simultaneously, improving the efficacy of treatments for complex diseases.
Registration Details
Terms & Conditions
- All fee paid is not refundable so please read all the terms & conditions before making any payments. If you still have any doubts please contact us and confirm and then only make the payment.
- Participants need to bring their registration tickets along with a valid Institutional ID, then only they will be allowed to attend the session. Please reach out to our team in case of any exceptions.
- Please fill all your details in the form correctly as those details will be used in your certificate as well.
- Participants need to bring their own computer (laptop) system for the program.
- The software tools and other required software tools will be provided from our side for the purpose of this program.
- Participants need to reach the venue and report 30 minutes prior to the start of the sessions.
- Participants need to wear masks all the time inside the premises and abide by the other rules at the premises.
- Particpants need to attend all the sessions in order to be eligible for getting the certificate.
- Welcome email will be sent to all the participants with all the details related to the program. Please check your Inbox/Spam folder for the email.
- All the details of the software installations and how to prepare your system for the Program will be shared with all the participants in the Welcome Email itself.
Contact Us
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